Say to them:
This is the nation that does not listen
to the voice of the LORD, its God,
or take correction.
Faithfulness has disappeared;
the word itself is banished from their speech.
(Jer 7:23-28)

If God calls you to do something for God in this world, you would think that it wouldn’t be a mission in vain. Sometimes we have to be faithful to what God has called us to, even though no one is listening.